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Appetite Suppression, Phentermine And Obesity Treatment

Over the last decade the problem of obesity has become so obvious that we can’t just ignore it. The number of obese people is increasing, not only among adults, but also among young people. Where does obesity come from? Now it has become clear that eating is not just a physical act. The modern world and lifestyle provide many reasons for obesity: stress and depression, unhealthy diet and lack of exercise, unhealthy food and lack of vacation time.

Studying the appetite of obese patients, scientists found a specific area of ​​the brain responsible for appetite. This includes the idea of ​​suppressing appetite by affecting these brain regions. Stimulants aimed at reducing hunger and through weight control are called amphetamines. They are thought to be addictive if taken for long periods of time, so they are available with a prescription.

In general, all drugs available on the market can be divided into two main pharmacological categories: those that affect the catecholamine pathway and those that affect serotonin. Anti-addiction drugs include phentermine, which has been shown to reduce hunger and reduce food intake, helping obese people stick to a low-calorie diet. It stimulates the circuit in the brain that increases blood pressure and heart rate in order to reduce appetite. Phentermine is relatively cheap and can be found on the Internet, which supports its popularity.

Phentermine prescription percentage reaches 50% due to its low price and effectiveness. In 1959 the FDA (Food and Drug Administration) approved phentermine as a short-term obesity treatment. Since then, phentermine has lived through periods of high popularity and times of decline and consumer distrust.

Fen-Phen and Dexfen-Phen, the combination of phentermine with fenfluramine and dexfenfluramine (or Redux) respectively, were the first drug cocktails to gain popularity. Although these compounds have never been approved by the FDA, they are legal because all of the ingredients have been approved by the FDA. The number of drugs reached 6.6 million at the end of 1996. A group of scientists at the University of Rochester under the leadership of Dr. M. Weintraub says Fen-Phen has no side effects and is more effective than regular exercise and diet.

However, despite the public excitement, there were no safety tests of these cocktails until 1997, when Mayo Clinic doctors faced 24 cases of heart attacks among Fen-Phen users. It caught the attention of the FDA and led to an extensive investigation. The test revealed that about 30% of Fenfluramine and Dexfenfluramine users have allergies, which exceeded expectations. These studies showed for the first time that valve dysfunction develops in patients who have taken drugs containing dexfenfluramine and fenfluramine for more than 6 months. As a result, Fenfluramine and Dexfenfluramine were withdrawn by the FDA in September, 1997. Note that the FDA did not request that Phentermine be withdrawn.

Today, phentermine is legal and only available with a prescription. Currently, it is available under the brands “Ionamin” and “Adipex-P” in pharmacies and on the Internet. A new cocktail containing phentermine is “Phen-Pro”. It is not believed to cause problems as a result of taking Fen- or Dexfen-Phens. “Pro” comes from Prozac, which is one of the following antidepressants: Calexa, Zoloft, Trazadone, Luvox and Effexor. This component is necessary to enable better functioning of phentermine in the long term and is not related to depression.

Finally, you should know that phentermine is an effective drug for the treatment of obesity available at a reasonable price. However, it is not a substitute for proper nutrition and training. Effective only with low-calorie diet and exercise. So now you know everything you need to know about phentermine, and we hope it will help you make the right choice on your way to a healthy and happy life!

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